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In Charleston, we have several local companies that are international and "home grown."
Blackbaud (fund raising software systems giant) began and remains here. Force Protection (manufactures the MRAP armored vehicle) local. We are becoming an information/tech hub more than a manufacturing center in Charleston. Several local tech/info systems companies support SPAWAR (the Naval Special Weapons Research Lab) here as well as the Naval Nuclear Power School. Many HR/Heath Care/Software firms choosing Charleston for headquarters because of the quality of life/beauty of the city.
The big boys are, however, from "off" - Boeing, Volvo, Mercedes here in the Charleston area and BMW in Greenville at the far north border.
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Try to rely on yourself as much as possible - when things go to hell, you will know who to blame.
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